Treatment continuity and early optimal management of Major Depressive Disorder provide the best opportunity for full recovery
Major Depressive Disorder is an often chronic and recurring illness. If left untreated, Major Depressive Disorder may result in progressive alterations in brain morphometry and circuit function.
In 2018, Oluboka and colleagues addressed this topic finding that pharmacotherapy may halt and possibly reverse those effects. These findings, together with evidence that a delay in treatment is associated with poorer clinical outcomes, underscore the urgency of rapidly treating depression to full recovery. Early optimized treatment, using measurement-based care and customizing treatment to the individual patient, may afford the best possible outcomes for each patient. Offering Major Depressive Disorder treatment determined by individual patient characteristics (e.g., predominant symptoms, medical history, comorbidities), patient preferences and expectations, and, critically, their own definition of wellness provides the best opportunity for full functional recovery.
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